Miscarriage and Flawed EggsI can't tell you the amount of literature I've read about older women, egg quality, and the higher chance of chromosomal abnormalities.
Here is an interesting article about how younger women may also have a high incidence of chromosomal problems. This article talks about how embryos of younger women (ages 21-31) were examined from donor cycles. I found it interesting that it's also possible that the chromosomal problems may be as a result of the IVF procedure itself or possibly the sperm:
Paulette Browne, at the Shady Grove Center for Preimplantation Genetics in Rockville, Maryland, US, and her colleagues, examined 275 embryos created from the donated eggs of women aged between 21 and 31. All the donors were ostensibly healthy. The researchers removed cells three days after conception and examined them for aneuploidies. They found that 137 - half - of the embryos had at least one error.
In a similar study, Nelson and colleagues looked at 289 embryos created using eggs from 22 donors under the age of 30. About 42% had chromosomal problems. "Initially, it shocked me," says Nelson. The studies were presented at a meeting of the American Society for Reproductive Medicine in Montreal, Canada, on Monday.from newscientist.com